CSF and the brain
A
The enlargement of the head may be a consequence of an abnormal increase in the quantity of CFS. The abnormal increase arises when there is an imbalance between the production rate of CFS, and the rate of dilation of cerebral ventricle – a condition also called hydrocephalus. In this condition, as from the case study, the periventrical white matter interstitial space of the brain accumulates fluid, which thus bulges to be seen as an enlargement of the head.
B
The best informatory test for this condition would be a CFS examination and MRI, as they quickly identify tumors. An MRI may precede CFS examination if the infant is suspected of having an intracranial or spinal mass lesion since they might lead to herniation. In other cases, a mass may be evident, where the lumbar puncture is useful after a few days to take control of the intracranial pressure. This must be clinically indicated.
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C
The 1st and 2nd and 3rd ventricles might be enlarged due to constriction in the cerebra aqueduct. Some CSF enters the subarachnoid space via the lateral and median apertures, thus causing enlargement or damage of both lateral and median ventricles. Nevertheless, the middle meninx, arachnoids mater, or arachnoid forms a loose brain covering, thus invisible. In case the arachnoid granulations were obstructed, then the subarachnoid villi would be enlarged, due to impaired absorption through the arachnoid villi.